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It is noteworthy that BPC 157 has a particular angiogenic effect in wound healing, which may also take place indirectly through the involvement of antioxidant enzymes

The concept draws from hormesis, a biological phenomenon where low-dose exposure to a substance produces beneficial effects while higher doses might produce neutral or even counterproductive outcomes

Historically, the obesity pharmacotherapy literature notes early trial signals and also that development was terminated after failure to show meaningful weight loss in a larger, longer trial (as summarized in a peer-reviewed review discussing a 12-week signal and a later 24-week negative result)

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But a Phase II randomised placebo-controlled hamstring-strain trial (NCT07437547) is registered, with no published results yet [8]